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Introduction. Currently most antibiotics are administered via the intravenous route.1 However, it has been observed in clinical practice that there are several situations where the necessary concentration of the administered antibiotic is not reached in the target tissue/system. A clear example of this clinical situation where optimal antibiotic concentrations are necessary is bone infection.

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No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the Data available Library of Congress Control Number2016936810 ISBN 9780199671328 practice, it is often used for any antibacterial; an antiparasitic is used to

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General Hospital G. Papanikolaou Thessaloniki, Greece Critical Care 2015, 19(Suppl 1):P10 (doi10.1186/cc14090) Introduction The aim of our study was to investigate perioperative risk factors associated with deep sternal wound infections in complicated cardiac surgery. Methods A total of 1,017 patients underwent cardiac surgery in a 2 year period.

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Anargiroi Hospital, Athens, Greece; 3 Medical School, Athens, Greece Critical Care 2013, 17(Suppl 2):P4 (doi10.1186/cc11942) Introduction The purpose of this study was to evaluate the immune response of patients susceptible to infection by Gram positive bacteria after ex vivo provocation with lipoteichoic acid (LTA) and to compare the

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